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VERSATILE MICROFLUIDICS PLATFORM

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Onyx is a microfluidic platform that enables researchers to seamlessly scale their liquid handling to high-throughput levels using microfluidics. With intuitive syringe pump control, high-speed microscopy, and active droplet manipulation, it supports both droplet and Semi-Permeable Capsule technologies. This flexibility empowers researchers to customize and optimize workflows, offering complete control without being limited to specific assays.

Compatible with

SEMI–PERMEABLE CAPSULES

Generation

DROPLET
MICROFLUIDICS

Generation

Generate

REAGENT ADDITION

Inject

Merge

Custom Microfluidic Modules

Onyx Brochure

Onyx Specifications

Syringe Pumps

A combination of 4 independent syringe pumps allows for controlled and precise injection of liquids into microfluidic chips.

Forcefield Generator

Utilizes a controlled electric field to manipulate droplets within microchannels, enabling active droplet manipulation modules, such as injection or merging.

Embedded UI

Provides users with an intuitive and interactive system to control and monitor experiments across multiple platforms, without the need for software installation.

Microscope Illuminator

An integrated 650nm light source offers controlled, adjustable illumination, and enhanced visibility without interference with photocleavable compounds.

High-speed Camera

Records dynamic processes within microfluidic channels at a rate of up to 4000 frames per second, enabling real-time observation of fast-paced events such as droplet formation.

Front

Integrated Microscopy

Enables imaging and tracking of microfluidic processes at a scale of 1μm/px and 1080p resolution.

Wi-Fi Antennas

Provide seamless connection to the device, enabling remote access to device software for convenience and flexibility.

Chip Holder

Securely anchors microfluidic chips during experiments and ensures accurate chip positioning for imaging.

Tube Holder

Securely contains and organizes collection tubes. Compatible with 0.2 mL, 0.5 mL, 1.5 mL and 2.0 mL.

Chip Adapter

Provides a user-friendly snap-on electrical connection to the chip, enabling active droplet manipulation without the need for brittle electrode pins or evaporating liquid electrodes.

Top

TOP OF THE LINE USER INTERFACE

In-line compartment size analysis

Displays compartment size and volume in real-time using machine learning

Occupancy analysis

Provides images of compartments in a collage format for visual verification of occupancy, helping adjust flow rate for optimal compartment loading

Uniformity monitoring

Collects image analysis data from compartments, enabling continuous monitoring of compartment size and volume to maintain monodispersity

Timelapse videos

Allows monitoring of cell growth and other dynamic processes over time

High-speed videos

Captures dynamic processes within microfluidic channels enabling real-time observation of fast events

Features

Integration

All-in-one microfluidics platform with an intuitive user interface

Flexibility

No reagent lock-in to design or modify any workflow

Functionality

Built-in image and experiment analysis capabilities

Convenience

Wireless connectivity for remote access and control

Portability

Can be used in cold rooms, anoxic chambers, laminar flow hoods and more

Accessibility

User interface access from any device, without software installation

Publications featuring Onyx

Systematic benchmarking of single-cell ATAC-sequencing protocols

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High throughput Single Cell Metagenomic Sequencing with Semi-Permeable Capsule: Unraveling Microbial Diversity at the Single-Cell Level in Sewage and Feces Microbiomes

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RNA cytometry of single-cells using semi-permeable microcapsules

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Single-cell barcoding and sequencing using droplet microfluidics

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Hydrop enables droplet-based single-cell ATAC-seq and single-cell RNA-seq using dissolvable hydrogel beads

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inDrops-2: a flexible, versatile and cost-efficient droplet microfluidic approach for high-throughput scRNA-seq of fresh and preserved clinical samples

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Workflow

DROPLET MANIPULATION MADE EASY

Reagents can be introduced post-droplet generation using high-voltage techniques. This process is streamlined with snap-on electrical connection, that ensures voltage flows directly to the required parts of the chip for reagent addition.